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Hyperion Therapeutics Announces Results Of Phase I Study In Patients With Liver Cirrhosis
Hyperion Therapeutics, Inc. announced top-line results from a phase I study of HPN-100 in patients with liver cirrhosis. The data were presented as part of the 2009 Digestive Disease Week meeting. The abstract is titled "Pharmacokinetic (PK) and Safety Analyses of a Novel Ammonia-Reducing Agent in Healthy Adults and Patients with Cirrhosis."
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Protein Level May Serve As Predictor Of Severe Osteoarthritis
Osteoarthritis (OA), the most common joint disorder throughout the world and a leading cause of disability, is characterized by pain, impaired joint mobility, reduction of muscular strength and loss of joint function. Unlike most other common diseases, little is known about its origins, and factors predicting a severe disease course have not been identified. A new study, the first to establish a laboratory marker for the risk of severe OA, found that vascular cell adhesion molecule 1 (VCAM-1), was a strong predictor of hip and knee joint replacement due to severe OA. The study was published in the August issue of Arthritis & Rheumatism .
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Medical Defence Union Supports Apologies To Patients But Says No Need For Duty Of Candour
Doctors already have a professional duty to provide patients with an explanation and apology when something goes wrong and the Medical Defence Union"s experience is that doctors do raise concerns and there is no need for a legal duty of candour. Each month the Medical Defence Union (MDU), takes several calls to its 24-hour advice line on the subject and opens files to assist medical members who want to raise concerns about patient safety.
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Advice For People With Asthma On Swine Flu Protection

Asthma UK"s team of clinical experts is offering important advice on how people with asthma can help protect themselves against swine flu now and into the autumn. - Make sure you use your preventer inhaler Adults and children with asthma are no more likely to contract swine flu than the rest of the population, but if they do get the virus, they could become unwell if their condition is not well-managed. It"s therefore vital that people with asthma ensure that they use their preventer inhaler (usually morning and evening), if they have been prescribed one. Cher Piddock, Clinical Lead at Asthma UK, says: "Some people with asthma stop using their preventer medicine as they don"t feel any immediate benefit, but it"s actually the most important medicine that you can use to prevent an asthma attack. Preventer medicine controls the swelling and inflammation in the airways and stops them from being so sensitive, but the protective effect builds up over a period of time so you need to take it every day, even when you"re feeling well." - Ensure that you don"t run out of your inhalers Mike Thomas, GP and Chief Medical Adviser to Asthma UK, says: "All the medicines that you have been prescribed are vital to keep your condition under control, so it"s essential that you"re organised and make sure you have a good supply." - Refer to your personal asthma action plan If you have a plan, refer to it regularly, as it provides details of all your asthma medicines and tells you what steps to take if your asthma gets worse, and what to do in an emergency. People with a plan are four times less likely to need hospital treatment for their asthma so, if you don"t have one, speak to your GP or asthma nurse for more information. - Prepare thoroughly before your holiday - and don"t forget insurance Wherever you go on holiday, it"s important that you take the same sensible precautions with your asthma that you would at home. If you"re travelling in Europe, it"s important that you take a European Health Insurance Card (EHIC) with you, which you can get from a Post Office. This will enable you to have any necessary medical treatment you need for free, including for swine flu. However, you will also need separate travel insurance before travelling. Many people with asthma find that getting specialist travel insurance can be difficult and expensive, but it"s essential that you have a policy in place before travelling abroad and that you check it covers asthma and swine flu. Mike Thomas continues: "Make sure you take a supply of your normal asthma medications on holiday, a peak flow meter if you have one and some simple over-the-counter cold and flu medications. It"s also important to find out where you can get medical help if you need it." - Try to lead a healthy lifestyle Keeping active and eating a healthy, balanced diet are important ways to keep asthma under control. Exercise can help to improve lung function and help with the management of asthma symptoms - studies have shown that people who exercise regularly seem to cope better with their asthma symptoms and have less need for their reliever inhaler. Diet also plays a key role, according to Cher Piddock: "Eating plenty of fruit and vegetables can help boost the immune system and help ward off colds and flu." If you think you may have swine flu, you should first go online and check your symptoms on http://www.nhs.uk or call the Swine Flu information line on 0800 1 513 513. Notes 1. Asthma UK is the charity dedicated to improving the health and well-being of the 5.4 million people in the UK whose lives are affected by asthma. 2. For up-to-date news on asthma, information and publications, visit the Asthma UK website http://www.asthma.org.uk. 3. For independent and confidential advice on asthma, call the Asthma UK Adviceline, which is staffed by asthma nurse specialists. It is open weekdays from 9am to 5pm on 0800 121 62 44. Or email an asthma nurse at http://www.asthma.org.uk/adviceline Asthma UK


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