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The Necessity Of Adrenalectomy At The Time Of Radical Nephrectomy: A Systematic Review
UroToday.com - To take the adrenal or not at the time of radical nephrectomy, that is the question. These researchers from New York University School of Medicine performed an extensive literature search to determine the role of adrenalectomy at radical nephrectomy and discovered that the incidence of solitary, synchronous, ipsilateral adrenal involvement, and therefore potentially curable tumor disease with ipsilateral adrenalectomy occurred extremely infrequently - in only 1% to 5% of cases.
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Also In Global Health News: Tanzania Drug Audit; WFP Might Suspend Flights; Acute HIV; HIV/AIDS In China
Global Fund Audit Reveals Expired, Missing Drugs In Tanzania
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As Flu Pandemic Declared, Leaders Must Focus On Poor Countries To Avert 'Bleaker Picture'
As the World Health Organization raised the pandemic alert for Influenza A (H1N1) to its highest level, humanitarian specialists are calling on governments and health authorities globally to strengthen poor communities" access to primary health care and protect the most at risk.
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Aiming For 'Below The Norm' Blood Pressure Offers No Benefit

Aiming for lower than standard blood pressure targets offers no known clinical benefit, according to a Cochrane Review. In a systematic review of the evidence, researchers found that using antihypertensive drugs to reduce blood pressure below the 140/90 mm Hg standard was not associated with any reduction in death rates or serious morbidity. "At present there is no evidence from randomized trials to support aiming for a blood pressure target lower than 140/90, in the general population of patients with elevated blood pressure," says lead researcher Jose Arguedas of the Faculty of Medicine at the University of Costa Rica in Costa Rica. The findings do not support guidelines in a number of publications that recommend aiming for lower targets, based on the assumption that "lower is better" when it comes to blood pressure. The researchers were unable to determine whether it is safe to aim for lower targets because relevant data was missing from most of the trials. The review is based on the results of seven trials, which together involved 22,089 people. Whilst patients aiming for targets below 135/85 mmHg did succeed in achieving greater reductions in blood pressure than those in the standard target group, there was no difference between the two groups in terms of the number of patients dying or suffering heart attacks, strokes, heart failure or kidney failure. "Our research included patients with diabetes or chronic renal disease, and the evidence was slightly less robust for those subgroups of patients. We intend to carry out separate systematic reviews for those subgroups, especially because guidelines recommend even lower blood pressure targets for them", says Arguedas. Jennifer Beal Wiley-Blackwell


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