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New Nanoparticles Could Revolutionise Therapeutic Drug Discovery
A revolutionary new protein stabilisation technique has been developed by scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) which could lead to 30 per cent more proteins being available as potential targets for drug development opening up exciting possibilities in drug discovery.
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President Obama Picks New York City Health Commissioner Thomas Frieden For CDC Director
President Obama on Friday appointed New York City Health Commissioner Thomas Frieden as CDC director, according to Obama administration officials, the New York Times reports. According to the Times, Frieden, an infectious disease specialist, has "cut a high and sometimes contentious profile" in his seven years as health commissioner in New York City, during which time he has advocated for a smoking ban in restaurants and bars, made HIV testing part of routine medical exams and protected a program that distributes 35 million condoms a year. According to the Times, Frieden is expected to take office next month. The Times reports that he will "inherit a host of immediate and long-term problems," including questions surrounding a vaccine for the H1N1 influenza virus, also known as swine flu, health care reform and organizational issues at CDC.The Times reports that a potential advantage for Frieden is a positive relationship with likely FDA Commissioner Margaret Hamburg, who also was New York City health commissioner. Frieden would work with Hamburg to combat the H1N1 flu virus and to re-evaluate the U.S. food safety system (Harris/Hartocollis, New York Times, 5/15).
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Payment Reform: A Trend In White House Thinking
White House health reformers have pressed over the last month for payment reforms that would reward doctors and hospitals for spending less and delivering higher quality care, rather than simply providing a higher volume of services. The Wall Street Journal reports that reexamining payment systems is a hot topic among administration officials in other disciplines, too: "President Barack Obama believes you get what you pay for--in business, in health care and in teaching. And in each of those spheres, he doesn"t think the way the U.S. pays professionals is designed to get what the nation really wants and needs."
Endocrinology

Cook Medical Announces FDA Clearance For Advance(R) 35LP PTA Balloon Dilatation Catheter

Cook Medical has received clearance from the U.S. Food and Drug Administration (FDA) to market its newest balloon dilatation catheter, the Advance® 35LP. The device is intended for use in patients with lesions in the femoral, iliac and renal arteries and rounds out Cook"s complete line of low-profile PTA balloons. The Advance 35LP will play an integral part in Cook"s Leg Therapy Program, an initiative geared toward helping physicians address the anatomical challenges of treating Peripheral Vascular Disease (PVD) and deliver clinically effective interventional solutions to the patients who need them most. Commonly associated with diabetes, hypertension and coronary disease, PVD can result in amputation or death if left untreated. Few are aware of the minimally invasive treatment options available apart from amputation or surgical bypass, the latter of which is the current gold standard in treating this disease. The Advance line comprises three low-profile balloons (14LP, 18LP, 35LP) that range in size and composition to treat lesions in the peripheral arteries as well as obstructive lesions of native or synthetic arteriovenous dialysis fistulas. The Advance 35LP balloon, compatible with a .035-inch wire guide, is designed to address common above-the-knee blockages. The Advance 18LP, compatible with a .018-inch wire guide, is geared toward the femoral artery and popliteal region of the leg. The Advance 14LP, compatible with a .014-inch wire guide, is reserved for treatment of the most tortuous anatomies of the lower leg, including the popliteal and infrapopliteal arteries. Each balloon features a low crossing profile and small-sheath compatibility, which helps reduce the need for an invasive arterial entry and may shorten patient recovery time. Advanced thermal setting of the balloon folds improves rewrap and sheath pull-back, and a unique double-lumen shaft construction using optimized nylon-blend material reduces balloon inflation/deflation time and improves pushability while maintaining kink resistance. Cook Medical


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