Popular Articles

HIV/AIDS Vaccine Coalition Urges Continued Funding For Research Amid Economic Crisis
A recently released AIDS Vaccine Advocacy Coalition report says that although there has been a renewed focus on discovery, innovation and basic science in vaccine research, action is needed to ensure that research funding continues during the economic downturn, VOA News reports. AVAC executive director Mitchell Warren said the report is "about putting all the pieces together ... not just the search for an AIDS vaccine, but in fact the entire HIV prevention response." He added, "[T]he good news is we have some new pieces of the puzzle, and we"re expecting additional new pieces of understanding through research this year." Warren said that AVAC believes HIV/AIDS vaccine research is in "one of the most exciting times," with "new energy, new commitment to unlocking some of the basic scientific roadblocks that have impeded our ability to find a vaccine." For example, a study released earlier this week examined efforts to produce a vaccine through genetic transfer. Regarding the study, Warren said, "It doesn"t mean we have an AIDS vaccine, but it means we have an entirely new approach to trying to deliver protection." Warren said that the field of HIV/AIDS vaccine research has shown a renewed commitment since Merck canceled its vaccine trial in 2007. According to Warren, the new AVAC report examines knowledge gained from the Merck study, which has provided "an unimaginable amount of information." Meanwhile, the effect of the economic crisis on research funding is concerning, Warren said, adding, "I believe that every dollar spent is going to be held up to a greater scrutiny as budgets tighten and as funders have to re-examine their priorities." According to Warren, without renewed funding commitments, "we will not only incur a much greater public health catastrophe, but I would argue that the economic catastrophes to come, if we don"t respond aggressively to HIV, will actually have repercussions that will ... make the economic crisis pale in comparison" (DeCapua, VOA News, 5/18).
generic viagra online
GTx Presents Phase II Ostarine (MK-2866) Cancer Cachexia Clinical Trial Results At Endocrine Society Annual Meeting
GTx, Inc. (Nasdaq: GTXI) announced results of a Phase II clinical trial evaluating Ostarine™ (MK-2866), an investigational selective androgen receptor modulator (SARM), in patients with cancer induced muscle loss, also known as cancer cachexia. In the study, Ostarine treatment led to statistically significant increase in lean body mass (LBM) and improvement in muscle performance measured by stair climb in patients with cancer cachexia compared to baseline in both the Ostarine 1 mg and 3 mg treatment cohorts. These study results were the subject today of an oral podium presentation at the 2009 Annual Meeting of the Endocrine Society in Washington.
News of the day
HPV Infection May Be Linked To Poor Head And Neck Cancer Survival In African Americans
A groundbreaking study in Cancer Prevention Research, a journal of the American Association for Cancer Research, suggests that having the human papillomavirus (HPV) improves survival in squamous cell carcinoma of the head and neck. Furthermore, African Americans had far less HPV infection than whites, which led to worse survival.
Cardiovascular

Exercise Programs Focusing On Muscle Density Could Reduce Disability And Hospitalization Of The Elderly

Older adults who have less strength, poor physical function and low muscle density are at higher risk of being hospitalized compared to adults with more strength and better function. That"s the finding of a new study in the Journal of the American Geriatric Society. The study also found that muscle density, a measure of how much fat compared to lean tissue there is in the muscle, is a more accurate gauge of a person"s risk of hospitalization than muscle mass or size. The relative risk for hospitizations was 50% higher for those with poor walking or less dense muscle mass "Our research suggests that we need to re-think the way we define sarcopenia or age-related muscle loss," says Peggy Cawthon, PhD, MPH, a scientist with the California Pacific Medical Center Research Institute and the lead author of the study. "Many definitions of sarcopenia today tend to focus on lean mass or muscle size, our study shows that is looking at the wrong factors. We found that muscle strength or performance were much better ways of measuring function." The researchers followed 3,011 healthy, non-disabled adults between the ages of 70 and 80, for an average of almost five years. They measured their physical function in a number of ways including walking speed, their ability to stand up from a chair repeatedly, the strength of their grip and their leg strength. By the end of the study more than 55 percent of the participants had experienced one or more hospitalizations. Those most likely to end up in the hospital were the adults who scored lowest on the measures of physical function; this held true after allowing age, medical conditions, lean mass or muscle size. They also found that adults with the least dense thigh muscles, namely those with a higher proportion of fat in their thighs, were also at a higher risk of hospitalization compared to adults with more dense thighs. "The findings are particularly important because they suggest that interventions, such as physical exercise, that improve physical function could help keep more vulnerable seniors out of the hospital," says Cawthon. "That would not only reduce disability but it would also reduce the huge economic burden associated with hospitalization of the elderly." One in five Americans over the age of 65 suffers from sarcopenia. In 2000 the direct health care cost of treating it were estimated to be more than $18.5 billion. With the number of Americans older than 65 estimated to double by the middle of the century those costs are expected to increase dramatically. Preventing older Americans from being hospitalized is more than just a matter of saving health care dollars, it may also save lives. Numerous studies show that even short stays in the hospital are associated with a greater future risk of functional decline and disability. "Most methods of measuring muscle mass or density rely on complex imaging procedures, such as using quantitative computed tomography (QCT). Those are time consuming and expensive," says Cawthon. "However, we found that much simpler methods - such as measuring walking speed - are much easier and cheaper to do, and are even more accurate in determining a person"s risk of future hospitalization. This gives us the ability to screen larger groups of people and help those at risk with some simple interventions, such as physical exercise." Jennifer Beal Wiley-Blackwell


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):