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California HIV/AIDS Advocates To Appear At Hearing On Proposed Budget Cuts
On Friday, HIV/AIDS advocates in California will appear at the state Legislature"s Budget Conference Committee hearing to urge lawmakers to block proposed health-related budget cuts, the Bay Area Reporter reports. According to the Reporter, Gov. Arnold Schwarzenegger"s (R) latest budget proposal includes cutting $67.8 million from state HIV programs and an additional $12.3 million from the AIDS Drug Assistance Program. Anne Donnelly of Project Inform said, "We realize we may have to take cuts to our programs. But let"s make sure they are minimized and that we continue to deliver the essential services to those people living with HIV and those also at risk." Next week HIV/AIDS advocates also plan to convene on the steps of the state Capitol to protest the proposed budget cuts (Bajko, Bay Area Reporter, 6/4).
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Keeping Older People Fit And Healthy - Older People's Prevention Package, UK
Simple measures such as good footcare, sight tests and light exercise can help older people live better, Care Service Minister Phil Hope said as he launched the Older People"s Prevention Package.
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Protecting The Heart With Glucocorticoid Drugs
Glucocorticoids are steroid hormones that have numerous functions; for example, they regulate the response to stress and suppress inflammation. Synthetic glucocorticoids are used clinically in many situations, most famously to treat asthma, allergies, and autoimmunity. They have also been shown in animals and humans to help protect the heart from the damaging effects of heart attack, and this has been attributed to their anti-inflammatory effects. However, Motoaki Sano and colleagues, at Keio University School of Medicine, Japan, have now determined another mechanism by which glucocorticoids protect rodent hearts from the damaging effects of heart attack. Specifically, glucocorticoids, acting via the glucocorticoid receptor (GR), induced mouse and rat heart muscle cells to produce PGD2, and this was responsible for the ability of glucocorticoids to reduce damage to mouse hearts in both an ex vivo and an in vivo model of heart attack. The authors therefore suggest that GR-selective glucocorticoids might be more beneficial to humans following heart attack than glucocorticoids that activate both GR and the MR protein, activation of which occurs in response to stress and might have unwanted consequences.
Public Health

First Novel H1N1 Influenza Cases Confirmed In Baldwin, Colbert And Dale Counties

The Alabama Department of Public Health has confirmed its first novel H1N1 influenza cases in Baldwin, Colbert and Dale counties. As of May 29, there are 85 confirmed and 9 probable cases of novel H1N1 influenza in the state. No deaths have been associated with the virus in Alabama. Counties and numbers of confirmed novel H1N1 cases which have been reported in their residents are as follows: Madison, 35; Montgomery, 8; Etowah, 7; Coffee, 6; Jefferson, 5; Shelby, 4; Lee, 4; Limestone, 2; Mobile, 2; Pike, 2; Baldwin, 2; Blount, 1; Colbert, 1; Dale, 1; and county to be determined, 5. The onset of the patients" symptoms occurred between April 20 and May 25. The ages of those affected range from 7 weeks to 45 years. Fifty-four of the state"s 85 confirmed cases are in children under 13 years of age. The median age of cases has increased to 10.5 years. Thanks to new laboratory equipment and a decline in the number of novel H1N1 influenza samples submitted, a backlog has been cleared. The symptoms of novel H1N1 influenza are similar to the symptoms of traditional influenza and include fever, cough, sore throat, body aches, headache, chills and fatigue. Some people have reported diarrhea and vomiting associated with novel H1N1 influenza. Close associates are advised to limit their contact with others for a period of seven days from the time they were exposed. The incubation period from the moment of exposure to novel H1N1 influenza until symptoms develop is two to seven days. Individuals are infectious to others one day before until seven days after symptoms develop. Persons who develop symptoms of respiratory illness should contact their medical provider. The department Web site at http://adph.org/H1N1Flu/ provides regular updates of case counts of novel H1N1 influenza within the state. Alabama Department of Public Health


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