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Invention Of Cooking Drove Evolution Of The Human Species, New Book Argues
"You are what you eat." Can these pithy words explain the evolution of the human species?
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Measles vaccination rates are still far lower than levels needed to protect the population. This is despite the finding of a new Department of Health survey that over 90 per cent of parents are aware it is the best way to protect their child.
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National Jewish Health And Ceragenix Announce Compound Shows Promise For Treating Potentially Lethal Viral Infections
Ceragenix Pharmaceuticals, Inc.("Ceragenix") (OTCBB:CGXP), a medical device company focused on infectious disease and dermatology, announced that researchers at National Jewish Health, led by Dr. Donald Y. Leung and Dr. Michael Howell, in collaboration with Dr. Paul B. Savage of Brigham Young University, have demonstrated in a series of in vitro experiments and preclinical animal testing that an investigational drug compound known as CSA-13 shows promise as a potential therapy to treat viral infections from the vaccinia virus. The research appears ahead of print in an advanced online publication of the Journal of Investigate Dermatology, the official journal of the Society for Investigative Dermatology. This work was funded by the National Institute of Allergy and Infectious Diseases Atopic Dermatitis Vaccinia Network.
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Rat Model Of Hepatic Encephalopathy And Prehepatic Portal Hypertension

A research article published in the World Journal of Gastroenterology refers. The research team lead by Dr. Gabriela Beatriz Acosta, observed that the activity of GS was increased in the hippocampus in PH rats. There was a significant decrease in glutamate uptake in both brain areas, which was more marked in the hippocampus. The decrease in glutamate uptake might be caused by deficient transport function and persistent glutamate activity, which is not metabolized. This leads to severe damage in the cells of the central nervous system (CNS), associated with the presence of moderate ammonia concentration in the blood, as observed in this model. These results demonstrated that partial stricture of the portal vein is able to modify normal function in important areas of the rat brain. These results suggest that, in PH this pathology, there are differences between both regions of the brain, possibly caused by the toxic metabolic action of ammonia and glutamate, and perhaps glutamine, in the brain, among other factors. Using this model, it may be possible to understand more clearly the mechanism of toxicity and defense of the brain against the two toxic substances: ammonia and the excitatory neurotransmitter glutamate. The study is important for understanding of some of the mechanisms related to HE. Reference: Acosta GB, Fernández MA, RosellĂö DM, Tomaro ML, Balestrasse K, Lemberg A. Glutamine synthetase activity and glutamate uptake in hippocampus and frontal cortex in portal hypertensive rats. World J Gastroenterol 2009; 15(23): 2893-2899 http://www.wjgnet.com/1007-9327/15/2893.asp Correspondence to: Dr. Gabriela Beatriz Acosta, Institute of Pharmacological Research (ININFA), National Research Council of Argentina (CONICET) and University of Buenos Aires, JunĂ­n 956. 5th floor, C1113AAD, Buenos Aires, Argentina. Lin Tian World Journal of Gastroenterology


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