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The Rewarding Aspects Of Music Listening Involve The Dopaminergic Striatal Reward
A Canadian research group has found that pleasure centers in the brain that respond to drug craving are also active when we listen to emotionally powerful music that gives us "chills" or "shivers-down-the-spine". Using two separate brain imaging tests the researchers examined subjects as they listened alternately to music that gave them chills and music that did not. Using a PET scan, the researchers showed that music that caused chills lead to a release of dopamine in the reward centers of the brain (mesolimbic striatum). Using fMRI on the same subjects, they found that activation in these regions happens both during the experience of chills and while subjects are anticipating them. Music, a mere sequence of notes arranged in time, can activate the same reward centers in the brain as drugs such as cocaine.
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Blood Pressure Association Comment On BMJ Research Paper
UK charity the Blood Pressure Association has responded to the BMJ research paper "Use of blood pressure lowering drugs in the prevention of cardiovascular disease":
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Annals Of Nutrition And Metabolism Publishes New Recommendations On Fat Consumption By 40 Of The World's Leaders In Diet Nutrition And Health
Reports published today in the Annals of Nutrition and Metabolism suggest that many people are confused about the health consequences of fats consumed. Often fat is not considered to be part of a healthy, balanced diet. Also many do not know that there are good, and even essential, fats. As a result, the quality of fats they consume is not in line with recommendations. To help overcome this problem, experts suggest that simple dietary changes be made, such as replacing full fat dairy (e.g. fatty cheeses) and meat products with lean choices, and use of fats and oils of vegetable origin rich in essential fats (sunflower oil, rapeseed oil, soybean oil and products made of these oils such as margarines) rather than of consuming fat of animal origin (lard, butter, etc).
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St. Jude Medical Announces Leading Sponsorship Of Landmark Clinical Trial To Study Atrial Fibrillation

St. Jude Medical, Inc. (NYSE:STJ) today announced that it is the leading sponsor of the Catheter Ablation Versus Anti-arrhythmic Drug Therapy for Atrial Fibrillation (CABANA) Trial. The pivotal trial, announced by Mayo Clinic, is intended to determine the effectiveness of catheter ablation (using long, narrow tubes to non-invasively reach and destroy abnormal heart tissue) in eliminating atrial fibrillation (AF), a condition in which the upper chambers of the heart beat quickly and erratically. "The results of the CABANA trial will be significant in shaping the future of cardiac ablation as a treatment and possible cure for AF," said Daniel J. Starks, Chairman, President and Chief Executive Officer of St. Jude Medical. "Supporting clinical trials like CABANA is an important part of our mission of advancing the practice of medicine through medical technology to help improve patient outcomes." The CABANA pivotal trial will last up to six years and will study the treatment of atrial fibrillation in a total of 3,000 patients and 140 centers from around the world. It will randomize patients over three years, with half undergoing catheter ablation and half receiving rate control or rhythm control drug therapy. Douglas Packer, M.D., a cardiologist at Mayo Clinic, will be the principal investigator of the clinical trial. Prior to the launch of this trial, Dr. Packer and Mayo Clinic led a 10-center, 60-patient pilot study. The results of this pilot study will be released later this summer. The CABANA Trial will be conducted in collaboration with the Heart Rhythm Service and Biomedical Imaging Res at Mayo Clinic, Rochester, Minn., Duke Clinical Research Institute, Durham, N.C., and CABANA Investigators. Mayo Clinic and Drs. Packer and Richard Robb, Ph.D., Mayo Clinic, have a financial interest in a mapping technology, licensed to St. Jude Medical, that may or may not be used in this research. St. Jude Medical


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