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New Study Results Published Compare ABRAXANE(R) To Taxotere(R)
Abraxis BioScience Inc. (NASDAQ:ABII) announced that final results from an open-label Phase II study evaluating three dose levels of the company"s chemotherapy agent ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin bound) compared to the highest standard dose of Taxotere (docetaxel) Injection Concentrate, in the first-line treatment of patients with metastatic breast cancer were published in the Journal of Clinical Oncology. According to investigator-assessed results, ABRAXANE administered weekly at 150 mg/m2 demonstrated an increase in progression-free survival (PFS) over docetaxel of 14.6 months versus 7.8 months, respectively (p=0.012). Results from the independent assessment of PFS for the 150mg/m2 treatment arm also demonstrated an increase in PFS (12.9 versus 7.5 months, respectively; p=0.0065). Investigators also noted a trend toward improvement in the study"s primary endpoint, overall response rate (ORR), confirmed complete and partial responses by Response Evaluation Criteria in Solid Tumors (RECIST) criteria with weekly ABRAXANE. In investigator-assessed results, the ORR was 74 percent for ABRAXANE 150 mg/m2 weekly arm (pAbout the Study
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Identification Of Brain Difference In Psychopaths
Professor Declan Murphy and colleagues Dr Michael Craig and Dr Marco Catani from the Institute of Psychiatry at King"s College London have found differences in the brain which may provide a biological explanation for psychopathy. The results of their study are outlined in the paper "Altered connections on the road to psychopathy", published in Molecular Psychiatry.
News of the day
Update Of Patient Experience PSA Scores, UK
The following statistics were released by the Department of Health: Patient experience PSA scores update based on data up to and including 2008 patient surveys. This publication updates the patient experience scores previously published on 24 November 2008. The patient experience PSA has been rolled forward as one of the indicators against "PSA delivery agreement 19: Ensure better care for all" for 2008-11. These figures report initial progress against the PSA target for sustained improvement in patient experience for the 2008-11 spending review period. Results are updated to include scores derived from survey results published by the Care Quality Commission in 2008. There are new data points for "adult inpatients" and "emergency department service users".
Diagnostics

UK's First Essenza Complements MRI Service At London Bridge Hospital

London Bridge Hospital, part of the HCA hospitals group, has installed the first Siemens MAGNETOM® Essenza MRI in the UK. The 1.5 Tesla system will complement three other Siemens MRIs currently in use at London Bridge to provide a streamlined, coordinated imaging service. The MAGNETOM Essenza is an efficient and reliable MRI solution. Short and lightweight, it incorporates the flexibility, accuracy and speed of Tim (Total imaging matrix) technology with a powerful new innovation, the IsoCenter Matrix coil. This unique, integrated coil makes patient setup faster and easier, eliminating the need for repositioning even during entire spinal scans. The Essenza will be used for a range of general imaging needs, enabling the hospital to offer more specialised imaging on the recently upgraded MAGNETOM® Symphony system already in place. As a result of this the hospital is now able to put plans for a cardiac stress service into operation. "The aim of the installation is to allow us to offer rapid access to MRI scanning within the group as well as provide a same-day imaging service," said Joe Cornall, Imaging Services Manager at London Bridge Hospital. "It was selected on the basis that it is a sound general scanner that ticked the box for weight requirements as well as featuring a short bore which is great for our claustrophobic patients." "The Essenza is fabulous as an additional scanner to accompany the systems we already have in place," said Patricia Clark, MRI Superintendent at London Bridge Hospital. "It"s also very patient-friendly - most of our lumbar spine scans can now be performed feet first which wasn"t possible before. With the new system we have also been able to shorten our waiting lists plus balance workloads more evenly across the MRIs." The MAGNETOM Essenza is integrated into the same centralised booking system as all other MRI systems in the group so that London Bridge Hospital can offer rapid access to scanning. "By installing a fourth Siemens MRI as part of the London Bridge Group, the hospital will be able to offer a faster, more effective service, scanning more patients and opening up new imaging opportunities on its existing systems," said Malcolm Pickering, Regional Sales Manager at Siemens Healthcare. "The MAGNETOM Essenza is the ideal high quality, cost effective imaging solution for this service and will maximise scanning efficiency." Siemens Healthcare


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