Public Health
The criteria used to assess blood alcohol concentrations (BACs) and binge drinking behaviors in children and adolescents should be based on pediatric rather than adult physiology, according to a new University of Pittsburgh study in the June issue of Pediatrics.
Bayer HealthCare LLC., Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX), OSI Pharmaceuticals, Inc. (Nasdaq: OSIP) and Roche today announced the initiation of a Phase 3 trial examining Nexavar(R) (sorafenib) tablets in combination with Tarceva(R) (erlotinib) tablets as a potential new treatment option for patients with advanced hepatocellular carcinoma (HCC), or primary liver cancer.
Poniard Pharmaceuticals, Inc. (Nasdaq: PARD), a biopharmaceutical company focused on innovative oncology therapies, today announced updated efficacy and safety data from its Phase 2 clinical trial of picoplatin in patients with metastatic castration-resistant (hormone-refractory) prostate cancer (CRPC). The data demonstrate that picoplatin in combination with docetaxel and prednisone is active as first-line therapy for metastatic CRPC. This was demonstrated by several endpoints, including reductions in prostate specific antigen (PSA) levels, disease control as measured by tumor response, and progression-free survival (PFS). Results also continue to show that picoplatin can be safely administered every three weeks for up to 10 cycles concurrently with full doses of docetaxel and prednisone, the standard treatment for CRPC. In addition, no neurotoxicity was observed in these patients.
In a sign of the challenges facing seniors on Medicare, a new study finds that older Americans are more likely to make poor choices when faced with a wide array of drug-coverage plans. Making matters worse, many are confident they made the right decisions.
Millions of Baby Boomers are struggling to care for their aging parents. Many don"t know where to turn or even what their options are in making important decisions about senior care facilities for their parents.
In research that could open new avenues of treatment for seasonal allergies, a team of Yale University scientists has discovered how a poorly understood component of the human immune system triggers - and sometimes worsens - allergic reactions. The research appears in the May 24 Advance Online Publication of Nature Immunology.
Abraxis BioScience Inc. (NASDAQ:ABII) announced that final results from an open-label Phase II study evaluating three dose levels of the company"s chemotherapy agent ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin bound) compared to the highest standard dose of Taxotere (docetaxel) Injection Concentrate, in the first-line treatment of patients with metastatic breast cancer were published in the Journal of Clinical Oncology. According to investigator-assessed results, ABRAXANE administered weekly at 150 mg/m2 demonstrated an increase in progression-free survival (PFS) over docetaxel of 14.6 months versus 7.8 months, respectively (p=0.012). Results from the independent assessment of PFS for the 150mg/m2 treatment arm also demonstrated an increase in PFS (12.9 versus 7.5 months, respectively; p=0.0065). Investigators also noted a trend toward improvement in the study"s primary endpoint, overall response rate (ORR), confirmed complete and partial responses by Response Evaluation Criteria in Solid Tumors (RECIST) criteria with weekly ABRAXANE. In investigator-assessed results, the ORR was 74 percent for ABRAXANE 150 mg/m2 weekly arm (pAbout the Study
The average U.S. family and their employers paid an additional $1,017 in health care premiums in 2008 to pay for care of the uninsured, according to a study released on Thursday by Families USA, USA Today reports (Kim, USA Today, 5/28). According to the study, which examined federal data, the uninsured received $116 billion in health care from hospitals, physicians and other providers in 2008 and paid 37% of that amount. Government programs and charities covered an additional 26%, which left another 37%, or about $43 billion, unpaid. The study then estimated how those costs are when spread across the insured through higher premiums, the study found. According to the study, prepared by the actuarial firm Milliman, the average additional amount paid under private coverage for single individuals was about $370 per year (Werner, AP/Austin American-Statesman, 5/28). Families USA Executive Director Ron Pollack said, "This is a hidden tax on all insurance premiums, whether it is paid by business for their work or by families when they purchase their own coverage" (USA Today, 5/28).The study is available online.
Many U.S. hospitals do not take sufficient disciplinary action against physicians for poor conduct or medical incompetence and fail to report such cases to the National Practitioner Data Bank, according to a report released Wednesday by Public Citizen, the Contra Costa Times reports. Congress established the databank in 1990 as a central repository for information about physicians whose hospital privileges had been withdrawn or limited for more than 30 days. The bank is closed to the public (Kleffman, Contra Costa Times, 5/27).For the report, Public Citizen"s Health Research Group analyzed studies by the HHS Office of Inspector General and the Citizen Advocacy Center, as well as medical journal articles and recommendations made during an October 1996 meeting on under-reporting by hospitals (Stark/Hallihan, ABCNews.com, 5/27). According to the report, nearly half of U.S. hospitals did not submit one physician"s name in 17 years to the databank. One purpose of the databank is to provide hospitals with background information about physicians they were considering hiring at their facilities. Under the initial expectations of the databank, federal officials estimated that at least 5,000 disciplinary cases would be reported annually. However, on average, about 650 reports have been made annually since the databank was created, the report found (Contra Costa Times, 5/27). The group on Wednesday sent a letter to HHS Secretary Kathleen Sebelius that included recommendations to improve the efficacy of the databank. The letter said that the reporting numbers are "unreasonably low, compared with what would be expected if hospitals pursued disciplinary actions aggressively and reported all such actions." The letter urged Sebelius to ensure that hospitals are conducting necessary peer reviews and oversight of physicians, taking proper disciplinary actions and reporting them to the databank so that physicians" track records are available to all hospital administrators. Penalties also should be established for hospitals that fail to comply with the reporting requirements, the group said.Al Levine, the author of the report, said some hospitals had found ways to avoid their physician reporting responsibilities, such as by limiting restrictions on hospital privileges to fewer than 30 days or giving physicians a "leave of absence" in place of suspending their privileges. Levine said, "Even in states with high levels of reporting," it "seems to be concentrated in a few facilities" (Contra Costa Times, 5/27).In a statement responding to the report, the American Hospital Association said, "The premise that the number of reports received by the National Practitioner Data Bank correlates to jeopardized patient care is inaccurate," adding, "Hospitals are actively involved in a wide variety of efforts to continuously improve care and talk publicly about the care we provide" (ABCNews.com, 5/27).
A coalition of ethnic minority advocacy groups has raised concerns that two of six budget-related propositions on the May 19 special election ballot would negatively affect minorities" health, New America Media reports. Proposition 1A would increase California"s cash reserve from 3% to 12.5% of state revenue and create a state spending cap. The measure also would extend recent tax increases for an additional two years. Proposition 1D would shift funds from First 5 California Children and Families Program, which provides health care services to children regardless of their immigration status, to the general fund.Cary Sanders -- director of Having Our Say, a coalition of 50 Asian, Hispanic and black organizations -- said, "If Proposition 1A and 1D pass, communities of color will have to shoulder the cost of our broken system because Proposition 1A limits our ability to invest in the health care system and Proposition 1D will result in more children becoming uninsured." Sanders noted that the First 5 program could reduce health and educational disparities.Quyen Vuong, executive director of the International Children Assistance Network, said Prop. 1D would cut $1.6 billion from the First 5 program. Julie Soderlund of Budget Reform Now, a committee campaigning in favor of the ballot measures, rejected arguments that Prop. 1D would compromise children"s health services. She added that the First 5 program accumulates $400 million in state funds and $2.1 billion in county funds, which she said could be put to good use by diverting them to the general fund to support human services. Alice Chen, a board member of the California Pan-Ethnic Health Network, said Prop. 1A could restrict minority communities" access to immunizations and dental and health services. However, Soderlund said that Prop. 1A would help prevent "roller coaster rides" in the state"s budget. State Assembly member Fiona Ma (D), who also supports the measures, said she is concerned that if the propositions fail, lawmakers would have to pursue other alternatives to close the budget gap, which could have an even worse impact on communities.Jan Robinson-Flint, executive director of Black Women for Wellness, raised concern over the legislative power Prop. 1A gives the governor over spending for programs. She asked, "Do we trust our current and future governors to do what"s right for our communities?" (Po/Ng, New America Media, 5/13).
A recently released survey on stigma in Rwanda indicates that at least 74% of people in various segments of society who have experienced discrimination are HIV-positive, the New Times/AllAfrica.com reports. The discrimination often is in the form of isolation from family and physical harassment, according to the survey. The study was conducted by the Association of Vulnerable Widows Infected and Affected by HIV and AIDS in conjunction with the Network of People Living with HIV and UNAIDS Rwanda. It found that although 87% of respondents reported never having been denied health services, 88% reported being denied other social services, such as family planning, because of their HIV status. An estimated one-third of respondents reported that their rights had been abused because of their HIV-positive status. Chantal Nyiramanyana, AVVAIS president, said, "We conducted this survey as a way of providing basis for advocacy, policy change, and programmatic interventions by the government and other interested bodies to address stigma and discrimination related to HIV." The survey found that other groups experiencing stigma in the country include commercial sex workers and asylum seekers (Kwizera, New Times/AllAfrica.com, 5/27).
American Indians in Alabama have better outcomes than the rest of the state"s population in some health indicators but are less healthy in other areas, according to a survey released by the Alabama Department of Public Health, the Montgomery Advertiser reports.The report -- titled "Health Survey of American Indians of Alabama 2008: Keeping the Circle Healthy" -- surveyed 3,000 people from the nine recognized tribes in the state. The study found that overall American Indians in Alabama had lower levels of obesity than the rest of the state and nation. The report also found that American Indians exercise more and eat more fruits and vegetables than the state"s general population. American Indians also reported that they smoke and binge drink less than the rest of the state. In addition, the report found lower rates of hypertension and arthritis among American Indians when compared with state and national populations. However, the report found that American Indians in Alabama consume more alcohol and have more strokes and heart attacks than other state residents. American Indians in the state also are less likely to undergo recommended screenings, such as Pap tests, mammograms and prostate exams, the report found. The report found that a high percentage of people in the state"s Piqua Shawnee and Ma-Chi"s Lower Creeks tribes lack health insurance. The report also found that two tribes have the capability to monitor health trends and provide preventive care. According to the Advertiser, the Poarch Band Creek is the tribe statewide that is federally recognized and has access to health services through the Indian Health Service. In addition, one tribe -- the MOWA Band of Choctaw Indians -- is recognized by the state and has a health clinic on its reservation. Ben Moreira, planning and economic development strategist for the Alabama Indian Affairs Commission, said American Indians represent about 1% of Alabama"s population. Moreira said he hopes the report will help American Indian tribes make decisions about health care res. "One of our primary goals is to get this survey into the hands of people who make the decisions about the allocation of health res in the state," he said, adding, "There is also a lot of information that is tribal specific that could be used to develop programs internal to each tribe" (Ricks, Montgomery Advertiser, 5/28).
Low vitamin D levels in blacks could contribute to health gaps between white and black U.S. residents, Michael Holick, a professor at Boston University and a vitamin D researcher, said recently, the GNS/Chicago Sun-Times reports. According to Holick, blacks have lower levels of vitamin D than whites in part because the higher amount of pigment in their skin makes it harder for their body to absorb the nutrient, which is produced in response to sun exposure. Although scientists are debating optimum vitamin D levels, some scientists have said that vitamin D can reduce the risk of cancer, diabetes, heart disease and other illnesses. Holick added that some scientists believe blacks are more likely to have prostate cancer, breast cancer and colon cancer and have more aggressive forms of the cancer because they have lower levels of vitamin D. John Flack, principal investigator at the Center for Urban and African American Health at Wayne State University, said lower vitamin D levels among blacks is "potentially a very important explanation for some of the differences, from hypertension to cancer to heart failure," adding, "The actual proof is not there, but it"s plausible." Flack added that many factors -- including decreased access to health care and differences in income and education -- contribute to the overall poorer health among blacks. The Institute of Medicine next year is expected to release new guidelines on recommended daily intake for vitamin D. "All Americans, but particularly people with darker skin, should pay attention" to the new guidelines, according to Adit Ginde, a researcher at the University of Colorado Denver School of Medicine who led a recent study that found vitamin D levels are decreasing in all racial groups and are particularly low in blacks (Painter, GNS/Chicago Sun-Times, 5/28).
Xiaoming, Xu, PhD, Associate Professor and Director of Biomaterials Research at LSU Health Sciences Center New Orleans School of Dentistry, has been awarded a grant in the amount of $1.77 million over four years by the National Institutes of Health to develop new antibacterial, fluoride-releasing, and bioactive dental materials including dental composites, bonding agents, and sealants. Currently most dental fillings and cosmetic restorations, including bonding and veneers, are done with resin-based dental composites - tooth-colored, plastic, and glass materials. Dr. Xu is working to develop the next generation of dental materials designed to reduce the secondary cavities that often develop around dental resin-based composite fillings as they shrink, causing them to fail. The new materials are expected to reduce secondary cavities and to prolong the life of restorations.
OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI) announced today that the Company will hold a live webcast and conference call of presentations made at an OncoGenex hosted reception during the 2009 American Society of Clinical Oncology Annual Meeting (ASCO) on Saturday, May 30, 2009. The webcast will begin at 7:10 p.m. EDT.
Portions of the brain that activate when people view pictures of objects compared to scrambled images can also be activated by touch alone, confirms a new report published online on May 28th in Current Biology, a Cell Press publication.
Drs. Timothy Halliday and Sally Kwak, economics professors at the University of Hawaii at Manoa, recently published a paper in Economics and Human Biology titled, "Weight Gain in Adolescents and Their Peers." The article examines trends in adolescent body mass index (BMI) in a nationally representative dataset.
In what could be a major pharmaceutical breakthrough, research published online in The FASEB Journal describes how scientists from St George"s, University of London have devised a one-two punch to stop HIV. First the report describes a new protein that can kill the virus when used as a microbicide. Then the report shows how it might be possible to manufacture this protein in quantities large enough to make it affordable for people in developing countries.
The Board of Somerset Primary Care Trust will be holding its next Board meeting at 10.00 am on Wednesday 3rd June 2009 at Wynford House, Lufton Way, Lufton, Yeovil. Somerset. BA22 8HR.
Researchers from the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine have uncovered a remarkable property of the contractile ring, a structure required for cell division. Understanding how the contractile ring works to divide the cell may facilitate development of therapies to prevent uncontrolled cell division in cancer.
As many as 700,000 people in the UK suffer from a heart abnormality
We all know that vitamin D and calcium are good for bones, but research teams in Europe and USA have shown that both taken daily reduces the rate of hip fracture in older people by 20%.
Clinicians, researchers and scientists from around the world will gather for Digestive Disease Week® 2009 (DDW®), the largest and most prestigious gastroenterology meeting, from May 30 to June 4, 2009, at the McCormick Place Convention Center, Chicago, IL. DDW is the annual meeting of the American Gastroenterological Association (AGA) Institute, the largest and oldest GI society in the world. AGA Institute researchers will present exciting, cutting-edge data during the meeting that will help change the way physicians diagnose and treat GI disorders.
The journal Human Reproduction reports the results of a survey which shows that ART (Assisted Reproduction Technology) is now responsible for 250,000 babies being born worldwide every year. The IFFS (International Federation of Fertility Societies), which represents most of the world"s fertility societies, has issued the following quote, which can be used as background material for any article on the Human Reproduction survey. This quote is embargoed to coincide with the Human Reproduction survey.
The Centre for Epidemiological Studies into Sexually-Transmitted Diseases and AIDS in Catalonia (CEEISCAT) started a pioneering study in Spain in 2005 to look into the prevalence of sexually-transmitted diseases (STDs) among female sex workers (SWs). The objective was to monitor the rates of infection with both HIV and other diseases over time, as well as the prevalence of risky behaviour.
At a time when breast augmentation tops the list for U.S. cosmetic surgical procedures, women are still left choosing between either the safety of saline or the natural result of silicone gel. Plastic surgeons are now looking to offer the best features of both in the revolutionary new technology of the IDEAL IMPLANT® Saline-filled Breast Implant. A clinical trial is launching this month in select markets nationwide, giving some women the opportunity to be among the first to have this new implant.
Laughter is not only an effective stress-reliever, but can be heart-healthy, according to research presented at the American College of Sports Medicine"s 56th Annual Meeting in Seattle. Two separate studies examined the role of a good laugh as it relates to health.
Frequent air travelers, as well as people who fly only occasionally, are often inconvenienced by the effects of jet lag, according to research presented today at the American College of Sports Medicine"s 56th Annual Meeting in Seattle. Christopher Berger, Ph.D., Chair of the American College of Sports Medicine (ACSM) Task Force on Healthy Air Travel, "Exercise is Medicine™ On the Fly," explains that jet lag, medically called desynchronosis, is the physiological response to alterations to circadian rhythms.
Amid concerns about a pandemic of swine flu, researchers from Nebraska report for the first time that poultry carcasses infected with another threat - the "bird flu" virus - can remain infectious in municipal landfills for almost 2 years. Their report is scheduled for the June 15 issue of ACS" semi-monthly journal Environmental Science & Technology.
Perceptive Informatics, the industry"s leading eClinical solutions provider and a subsidiary of PAREXEL International Corporation (Nasdaq: PRXL), announced the launch of a website designed to help investigators apply the new 1.1 version of RECIST (Response Evaluation Criteria In Solid Tumors) in medical imaging-based oncology trials.
APS Healthcare, a leading provider of specialty healthcare solutions, has been selected by the Oregon Department of Human Services (DHS), Division of Medical Assistance Programs, to manage its statewide Medicaid disease and medical care management programs. The integrated program will assist Oregon"s Medicaid and SCHIP fee-for-service clients to access healthcare, minimize catastrophic health events and improve health outcomes through education and interventions that help promote behavior change.
Not yet convinced about keeping your healthy teeth, here"s another reason.
Whether it"s "powdering your nose" or settling in for a good read, Americans spend a significant amount of time in the bathroom. According to a recent Yankelovich survey, many Americans spend more than 30 minutes each day in the bathroom that adds up to nearly eight days each year - which is more than double that of the average vacation trip . And contrary to popular belief, men spend almost as much time in the bathroom as women.
In the May 15th issue of G&D, Dr. Ting-Fen Tsai (The National Yang-Ming University, Taiwan) and colleagues present a new animal model of human Wolfram Syndrome, and effectively link CISD2 gene function, mitochondrial integrity and aging in mammals.
The FDA is ignoring critical information in deciding whether to approve an over-the-counter, rapid HIV test for home use, according to a recent article in the journal Medical Decision Making (MDM) which is published by SAGE.
White House Press Secretary Robert Gibbs on Thursday assured abortion-rights groups that Supreme Court nominee Judge Sonia Sotomayor shares President Obama"s views on constitutional protection for a right to privacy and a woman"s right to abortion, the Washington Post reports. Although many abortion-rights groups have welcomed the nomination, some have voiced concern over Sotomayor"s limited judicial record on cases involving abortion rights, especially the right to privacy that forms the basis for Roe v. Wade. Gibbs said that although Obama did not specifically ask Sotomayor about abortion rights during preliminary interviews, the White House is certain she agrees with the president on the constitutionality of Roe. Obama and Sotomayor "talked about the theory of constitutional interpretation, generally, including her views on unenumerated rights in the Constitution and the theory of settled law," Gibbs said, adding that Obama felt "very comfortable with her interpretation of the Constitution being similar to that of his." In a 2007 campaign debate, Obama said he would not nominate "somebody who doesn"t believe in the right to privacy," which the Supreme Court ruled gave women the right to terminate a pregnancy. Obama administration officials also said that they held private conversations on Thursday with groups on both sides of the abortion debate.The Post reports that Sotomayor has not dealt with constitutional issues regarding abortion rights in the nearly two decades she has been a federal judge. Her most notable decision regarding abortion was in 2002 when she ruled that the Bush administration had the right to implement the "global gag rule," which banned federal funding for international family planning groups that offer abortion services and information. Although that decision "reveals nothing about abortion rights," it is based on precedents from the Supreme Court and the Second U.S. Circuit of Appeals, the Post reports. Sotomayor wrote in her decision that the Supreme Court "has made clear that the government is free to favor the antiabortion position over the pro-choice position, and can do so with public funds." She also ruled that a group of antiabortion-rights protesters could go forward with a lawsuit alleging police brutality; however, that case focused on issues of municipal liability, not the constitutional right to an abortion, according to the Post.Currently, the court is essentially split on the issue of the right to privacy and abortion. Retiring Justice David Souter was one of three authors in a 2002 decision that upheld the basic tenets Roe, and abortion-rights supporters believe that replacing Souter with someone who does not support Roe would threaten those rights, the Post reports. Senior Senate Democrats said that they expect the issue to be brought up during private meetings with Sotomayor next week. However, Sen. Barbara Boxer (D-Calif.), a strong supporter of abortion rights, said she will not specifically ask Sotomayor about Roe. She said that she "feel[s] as comfortable as I could possibly feel" about Sotomayor"s support for abortion rights (Barnes/Shear, Washington Post, 5/29). Advocates on both sides of the abortion-rights debate are urging members of the Senate Judiciary Committee to question Sotomayor about her views during her confirmation hearings. Nancy Northup of the Center for Reproductive Rights said, "I think both sides can agree that the American people should know where its nominees to the Supreme Court stand on important constitutionally decided decisions like Roe v. Wade." Charmaine Yoest, president of Americans United for Life, said, "We"ve really been focused on asking senators to really probe this question of her judicial philosophy, as to whether or not she"s going to approach a decision like [Roe] as a jurist or as a woman" (Totenberg, "All Things Considered," NPR, 5/28). Douglas Johnson, legislative director of the National Right to Life Committee, said his group thinks it is "critical that senators thoroughly explore whether [Sotomayor] b
The Obama administration"s draft guidelines outlining criteria for federal funding of stem cell research "go only halfway toward freeing embryonic stem cell research" because "[s]ome of the most promising investigations will still be denied federal funding," syndicated columnist Froma Harrop writes in a Providence Journal opinion piece. Harrop writes that although "the public supports the research by more than two to one," there is "a vocal minority opposed to this work because it requires the destruction of embryos." According to Harrop, although Obama allowed research on embryos willingly donated by fertility clinic patients and lifted former President George W. Bush"s restrictions limiting federal funding to research on 21 existing stem cell lines, he "wouldn"t budge on the prohibition against funding research that allows for the creation of embryos out of human cells," known as therapeutic cloning. She notes that "therapeutic cloning has little to do with human cloning, which is about making new people and is illegal most everywhere. But say that cloning is being used in research, and many folks think they"re going to have a clone as a neighbor in a few years."Harrop continues, "[B]y allowing the use of embryos from fertility clinics and not those created by researchers, the administration lends credence to the view that embryos are full human beings." However, the "only difference between embryos in fertility clinics and the ones cloned for research is the motive of the people who created them." She concludes, "Obama"s timidity in rewriting the guidelines has slowed down important research and produced more confusion. And for Americans praying for cures from this science, the choice seems rather clear" (Harrop, Providence Journal, 5/28).
The opportunity to enact health care reform legislation could be missed unless Congress passes it this year, President Obama on Thursday said to thousands of supporters in a phone call made from Air Force One, the AP/USA Today reports. In a call to members of his political organization, Organizing for America, Obama said, "If we don"t get it done this year, we"re not going to get it done," adding, "I think the status quo is unacceptable and that we"ve got to get it done this year." Obama also said that any action on overhaul legislation could be delayed unless volunteers pressure lawmakers to support the administration"s goals for health care reform (AP/USA Today, 5/28). Obama said, "Some of you are in states and districts where politicians are resistant to bringing about change, so we need you to get involved" (Zeleny, "The Caucus," New York Times, 5/28). Obama told volunteers that it was time to "remobilize" after their successful campaign to get him elected, adding that "we have gotten a lot of things done during our first four months. But health care, that"s a big push" (AP/USA Today, 5/28).David Plouffe, Obama"s presidential campaign manager and head of Organizing for America, during the call said, "If the country stands with the president and if the country is demanding health care reform, [then] we"ll get it done," adding, "Washington will not have any option but to follow us." He added, "You need to take ownership of this" ("The Caucus," New York Times, 5/28). Organizing for America Campaign
As long as there have been babies, adults have crooned lullabies to soothe them. But research suggests music might also help premature infants learn to suckle better and reduce their pain.
GTCbio Announces 4th Annual Assay Development and Screening Conference taking place June 8-9, 2009. As compounds derived from high throughput screening increasingly find their way into clinical trials, drug screening has become widely accepted as a critical step in the drug discovery process. After more than a decade of rapid growth, tremendous progress has been made in assay technology, laboratory automation, and informatics. These technological developments have not only facilitated a drastic increase in throughput and efficiency in drug screening, but have also provided novel solutions in other areas of drug discovery and development. As screening has also become prominent in biological research, screening facilities have become increasingly popular in academic institutions.
Minutes after receiving a single, powerful non-invasive radiosurgery treatment, John Sisco, 64, happily walked out of the treatment room without any need for an overnight stay in the hospital, and left for home. Doctors at Somerset Medical Center, in Somerville, New Jersey, used the advanced Novalis Tx™ platform from Varian Medical Systems (NYSE: VAR) and BrainLAB to deliver the accurate, image-guided treatment designed to eradicate an abnormal tangle of blood vessels, called an artereo-venous malformation (AVM), that had grown near Sisco"s brainstem.
A new article published in Elsevier"s journal Bioscience Hypotheses suggests that our feelings in our lifetime can affect our children.
A new study showed that the breast cancer drug Herceptin improved survival in patients with HER2-positive stomach cancer, an aggressive form
Patients with inflammatory arthritis completing a health-related quality of life questionnaire report levels of pain that result in their health being rated as "worse than death" by members of the general population.
G-20 leaders pledged to provide the International Monetary Fund with $500 billion to help struggling economies, sparking global controversy. Yet startling research shows that the combined costs of tobacco-related death and related productivity losses, healthcare expenditures, employee absenteeism, and widespread environmental harm are responsible for draining the same amount - $500 billion - from the global economy each year and it receives much less attention than it deserves.
The Alabama Department of Public Health has confirmed its first novel H1N1 influenza cases in
A survey of trauma patients reported in the Medical Journal of Australia has found that compensation-related factors are significant predictors of health care utilisation.
The Regulatory Affairs Professionals Society (RAPS), the world"s largest
Osteoporosis, or bone loss, is a disease that is most common in the elderly population, affecting women more often than men. Until now, it was not clear exactly how the disease develops. Researchers of the Max Delbr̿ck Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have now elucidated a molecular mechanism which regulates the equilibrium between bone formation and bone resorption. Dr. Jeske J. Smink, Dr. Val̩rie B̩gay, and Professor Achim Leutz were able to show that two different forms of a gene switch - a short isoform and a long isoform - determine this process. The MDC researchers hope these findings will lead to new therapies for this bone disease. (EMBO Journal)*.
With consumer genetics becoming more of a reality to the average consumer and direct-to-consumer (DTC) genetics tests becoming more available, thought leaders, experts and DTC companies will convene in Boston on June 9-11 for the first annual Consumer Genetics Conference to move the issues to the forefront and demystify this emerging field. Preeminent leaders from government, healthcare, biotechnology and diagnostic fields, will examine consumer genetics, including its practical realities and complex policy considerations; speakers and companies will present new advances and information on available genetic tests and developments in this field. The conference is open to all who are curious, impacted by, and interested in consumer genetics, including consumers (http://www.consumergeneticsconference.com).
The Honourable Leona Aglukkaq, Minister of Health, and the Honourable Jim Prentice, Canada"s Environment Minister, today announced the release of the draft screening assessments and risk management scope documents for 18 substances assessed in Batch 6 of the Chemicals Management Plan. The Government has reached the halfway point in its commitment to assess approximately 200 high-priority substances as part of the Chemicals Management Plan.
The Royal College of Physicians (RCP) in partnership with Birkbeck College and the London School of Hygiene and Tropical Medicine, has launched a new Masters Degree in Medical Leadership. The programme is aimed at doctors aspiring to leadership roles within the health sector, such as Clinical Directors, Medical Directors or Chief Executives.
The ANF calls on the Prime Minister to consult with nurses and other occupations that are most affected before implementing changes to the retirement age for pensions or superannuation.
People with macular degeneration gradually lose their central vision - they find it harder to see things that are directly in front of them - making it much harder to read, write, recognize faces and drive. The macula, or macula lutea (Latin: macula = spot + lutea = yellow) is an oval shaped yellow spot near the center of the retina of the eye. Macular degeneration mainly affects elderly people. It is caused by damage to the retina.
ACCESS PHARMACEUTICALS, INC.(OTC Bulletin Board: ACCP), provided an update on the progress in the Company"s clinical development plan for ProLindac, a novel DACH platinum drug that has shown to be active in many solid tumor types in human clinical studies. Access recently announced positive safety and efficacy results from its Phase 2 monotherapy clinical study of ProLindac(TM) in late-stage, heavily pretreated ovarian cancer patients. In this study, 66% of patients who received the highest dose achieved clinically meaningful disease stabilization according to RECIST criteria. No patient in any dose group exhibited any signs of acute neurotoxicity, which is a major adverse side-effect of the approved DACH platinum, Eloxatin, and ProLindac was well tolerated overall. The Company has scaled up manufacturing in order to begin the next phase of clinical development. Access plans to conduct several combination trials in different solid tumor types both as Company-sponsored trials and in conjunction with its two previously announced co-development partners.
Neurobiological Technologies, Inc. (Nasdaq: NTII) (NTI(R)) announced that Celtic Pharmaceutical Holdings L.P. (Celtic Pharma) has announced the results from its Phase 3 Clinical Program for XERECEPT(R) in patients with edema associated with brain tumors and from preclinical studies of XERECEPT in brain tumor models.
New research quantifies the precise effects of environmental pollutants and alcohol intake on gastrointestinal (GI) health. Both studies being presented this week during Digestive Disease Week® 2009 (DDW®) offer concrete evidence that the environment and alcohol intake can affect GI health and share important insights into new directions for future research. DDW is the largest international gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.
Researchers from the Peninsula Medical School and the University of Bristol, using data from the Avon Longitudinal Study of Parents and Children and the Exeter Family Study of Childhood Health, have identified a common genetic variant that explains why some women may find it more difficult to quit smoking during pregnancy.
The Pima County Health Department is releasing additional
AnaSpec has announced the launch of the industry"s first FRET-based thrombin assay - the SensoLyte 520 Thrombin Activity Assay Kit.
Time is short for scientists to respond to the call for comments on the National Institutes of Health (NIH) proposed guidelines for the use of human embryonic stem (ES) cell lines and their eligibility for federal funds. On May 26, the window to provide feedback will close, and the drafted rules leave the possibility that funding for almost all existing cell lines will disappear.
Several Republican senators in appearances on various talk shows on Sunday said that they do not expect the GOP to attempt a filibuster to block the Supreme Court nomination of Judge Sonia Sotomayor, although none ruled the idea out, the Washington Post reports. Sen. Kay Bailey Hutchison (R-Texas) said that she does not think the "need for filibuster will be there unless we have not had a chance to look at the record fully," adding that the Senate "need[s] to look at the record fully" and in an "expeditious way." Sen. Jeff Sessions (R-Ala.), the ranking member on the Senate Judiciary Committee, on NBC"s "Meet the Press" said that Sotomayor"s 17-year career as a federal judge is "very strong in her favor" and "the kind of background you would look for" in a Supreme Court justice. However, Sessions added that he and other Republican senators are concerned over a remark Sotomayor made in 2001 at a conference on Hispanics in the judiciary. According to the Post, Sotomayor was discussing how her Puerto Rican heritage has influenced her role as a judge when she said, "I would hope that a wise Latina woman with the richness of her experience would, more often than not, reach a better conclusion than a white male who hasn"t lived that life." Sessions said the remark "goes against the heart of the great American heritage of an independent judge" (Barnes, Washington Post, 6/1). Judiciary Committee member John Cornyn (R-Texas), appearing on ABC"s "This Week," said that senators "need to know ... whether she"s going to be a justice for all of us or just a justice for a few of us" (Wallsten, Los Angeles Times, 6/1).Sen. Charles Schumer (D-N.Y.) -- Sotomayor"s sponsor through the confirmation process -- said on "This Week" that she is "virtually filibuster-proof when people learn her record and her story." He added that Sotomayor is "legally excellent" and "not a far-left-wing judge" (Barnes, Washington Post, 6/1). White House Defends Sotomayor"s Comments White House Press Secretary Robert Gibbs said that he thinks Sotomayor would "say that her word choice in 2001 was poor, that she was simply making the point that personal experiences are relevant to the process of judging." In an interview with NBC News that will air this week, President Obama also defended Sotomayor, saying that "if you look in the entire sweep of the essay that she wrote, what"s clear is that she was simply saying her life experiences will give her information about the struggles and hardships that people are going through" (Eggen/Kane, Washington Post, 5/30). Obama also stood by his decision to nominate Sotomayor in his weekly radio and Internet address on Saturday. Obama said that he is "certain that she is the right choice" and that her record as a federal judge "makes clear that she is fair, unbiased and dedicated to the rule of law." While he said he expects "rigorous evaluation" of Sotomayor, Obama said his "hope is that we can avoid the political posturing and ideological brinkmanship that has bogged down this process, and Congress, in the past" (AP/USA Today, 6/1). First Meetings With Senators Expected This WeekAccording to the AP/Chicago Tribune, Sotomayor is scheduled to hold her first meetings with senators this week, beginning on Tuesday with Sessions and Democratic Sens. Harry Reid (Nev.) and Judiciary Committee Chair Patrick Leahy (Vt.). Gibbs said a meeting with Senate Minority Leader Mitch McConnnell (R-Ky.) also is possible, adding that he is hopeful there will be other meetings scheduled throughout the week (AP/Chicago Tribune, 5/31).The Wall Street Journal reports that the formal Senate confirmation hearings are not expected to begin for several weeks. The White House would like the Senate to confirm Sotomayor before the August recess so she will be on the bench for the court"s next term, which begins in October. Although some GOP senators say this might not be enough time to fully examine her record, Sotomayor is expected to be confirmed, the Journal reports (Bendavid, Wall Street Journal, 6/1).
The Institute of Medicine and the National Research Council on Thursday issued revised U.S. weight-gain guidelines for obese pregnant women, in response to rising levels of obesity in the country and growing evidence that weight gain can cause health problems for women and their infants, the New York Times reports. The revision, which is the first since 1990, recommends that obese women -- those with a body mass index of 30 or more -- limit their weight gain to 11 to 20 pounds over nine months. The 1990 pregnancy guidelines did not specifically address weight gain for obese women, telling them instead to follow the recommendations for overweight women. According to health officials, the changes to the recommendations for obese women were required to keep up with the changing weight patterns among women in the U.S. The New York Times reports that about 27% of women of childbearing age are considered obese, while 55% fall into the categories of overweight or obese.The recommendations for women with BMIs of less than 30 did not change. They call for overweight women -- those with a BMI of 25 to 29.9 -- to gain 15 to 25 pounds over nine months, while underweight women -- with BMIs of less than 18.5 -- should gain 28 to 40 pounds, and normal-weight women -- with BMIs of 18.6 to 24.9 -- should gain 25 to 35 pounds (Parker-Pope, New York Times, 5/29).Time reports that pregnant women who do not gain enough weight face a higher risk of stunted fetal growth and preterm delivery. However, it is more common for women to gain too much weight, placing them at higher risk for conditions like gestational diabetes and high blood pressure. In addition, their infants are at increased risk of being born earlier, larger and by cesarean section. Time reports that excessive weight gain can increase a woman"s risk of postpartum obesity and elevate risks of heart disease and stroke because most women do not lose extra pounds gained during pregnancy. Many studies also have suggested that a woman"s gestational weight can predict potential weight problems in her offspring (Kingsbury, Time, 5/28).The committee that developed and issued the revision said that the existing guidelines were essentially on target but that women and their physicians need to work harder to help women reach a normal weight before pregnancy and avoid gaining too much weight during pregnancy, according to the Los Angeles Times (Roan, Los Angeles Times, 5/29). The guidelines also recommend more nutrition and exercise counseling during pregnancy, advising physicians or midwives to consult dieticians to shape a woman"s care regardless of her initial weight, the AP/Yahoo! News reports (Neergaard, AP/Yahoo! News, 5/28). The Los Angeles Times reports that health care professionals are expected to recognize and implement some of the recommendations; however, it is not mandatory to do so.Several experts on maternal obesity and child health expressed disappointment with the guidelines, arguing that obese women should gain little to no weight during pregnancy, according to the Los Angeles Times. They also argue the new guidelines do not do enough to address obesity before pregnancy. Maxine Hayes, state health officer for the Washington State Department of Health, said, "If we wait for every woman to be advised about weight gain after they become pregnant, it"s too late. It puts women and their babies on a trajectory that is unhealthy" (Los Angeles Times, 5/29).
Stem cells containing protective genes may provide permanent control of human immunodeficiency virus (HIV) in infected individuals, according to research presented at the American Society of Gene Therapy 12th Annual Meeting, May 30.
A new study examining treatment decision-making by older women with early stage breast cancer shows that 45 percent of women would choose to get chemotherapy after surgery -- a figure higher than the national average of women getting the additional treatment.
The four-type (6,11,16,18) human papillomavirus (HPV) vaccine, Gardasil®, has been chosen by the Norwegian authorities for the national vaccination programme after the assessment of a variety of criteria, including efficacy in the prevention of cervical cancer, safety and evidence of long-lasting protection. All available data was considered, including new data presented during the 25th International Papillomavirus Conference (IPC) in May in Malmç¶, Sweden.
The latest advances in polyp detection, assessment of colorectal cancer risk, and patient sedation during colonoscopy will be presented today at Digestive Disease Week® 2009 (DDW®). Research regarding the size and type of polyps detected during colonoscopy and the risk associated with developing colon cancer offers new insight into the recommended frequency of follow-up preventive colonoscopy. New research also examines the risk of perforation during colonoscopy and new tools allowing physicians to more closely examine polyps during colonoscopy including optical biopsy and deep sedation of the patient will be presented. DDW is the largest international gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.
Daqing Li and colleagues, at the University of Pennsylvania School of Medicine, Philadelphia, have identified in vitro and in mice a way to enhance the anticancer effects of the commonly used platinum-based drug cisplatin.
Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), today announced
UCB announced that the European Medicines Agency"s (EMEA) Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion recommending that the European Commission lifts the treatment restrictions for Neupro® (rotigotine transdermal patch) in Europe.
Tiny fluctuations in a fetus"s heartbeat can indicate distress, but currently there is no way to detect such subtle variations except during labor, when it could be too late to prevent serious or even fatal complications.
If having malodorous armpits (called osmidrosis) and goopy earwax isn"t bad enough, a discovery by Japanese scientists may add a more serious problem for women facing these cosmetic calamities. That"s because they"ve found that a gene responsible for breast cancer causes these physical symptoms. The report describing this finding is featured on the cover of The FASEB Journal"s June 2009 print issue, and should arm physicians with another clue for detecting breast cancer risk.
It is commonly known that alcoholism and alcohol intoxications are connected with severe violent crimes such as homicides. For instance, in Finland even 80 per cent of these crimes happen in alcohol intoxications. It has not, however, been clear why only a minority of alcoholics in intoxications become irritated and impulsively aggressive or even commit severe violent crimes.
ImmunoGen, Inc. (Nasdaq: IMGN), a biopharmaceutical company that develops targeted anticancer therapeutics, announced the presentation of encouraging trastuzumab-DM1 (T-DM1) clinical data at the 2009 Annual Meeting of the American Society of Clinical Oncology (ASCO) taking place in Orlando, Florida.
"Health industry officials delivered a plan to the White House Monday documenting how they"ll attempt to save $2 trillion over a decade through measures like reducing hospitalizations and cutting down on paperwork," the Associated Press reports. "Health insurers, doctors, hospitals, drug-makers and others were under pressure to make good on a pledge they made last month to curb their own costs to help President Barack Obama achieve his health care overhaul goals." Their three big areas of savings: $150 billion to $180 billion would come from more efficient use of health care services, $350 billion to $850 billion from better management of chronic diseases, and $500 billion to $700 billion through administrative improvements such as standardizing claim forms (Werner, 6/1).
Congress is returning from its Memorial Day recess Monday with plans to begin examining proposals in earnest for what health care reform in America will look like, The Associated Press reports.
Biologic disease-modifying antirheumatic drugs (DMARDs) such as adalimumab, etanercept and infliximab are effective at reducing symptoms and slowing progression of rheumatoid arthritis (RA). These drugs act more quickly, require less laboratory monitoring, and are better tolerated than nonbiologic DMARDs, but they are also up to 100 times more expensive. Insurance plans differ greatly in their coverage of and cost sharing for biologic DMARDs, sometimes shifting a large portion of the cost of patients. A new study examined the cost-sharing structures for biologic DMARDs in Part D plans and the resulting cost burden to patients. The study was published in the June issue of Arthritis Care & Research.
A new multi-center study, conducted at The Feinstein Institute for Medical Research in collaboration with five other centers throughout the country, tested the commonly prescribed antidepressant citalopram and found that it was no more effective than placebo in altering obsessive features of the condition - the spinning, rocking and repetitive behavior.
Virginia Commonwealth University researchers have identified a gene that may play a key role in regulating tumor progression in neuroblastoma, a form of cancer usually found in young children. Scientists hope the finding could lead to an effective therapy to inhibit the expression of this gene.
Cougar Biotechnology, Inc. (NASDAQ:CGRB) announced that results from ongoing Phase II clinical trials of Cougar"s investigational drug CB7630 (abiraterone acetate) were presented at the 2009 ASCO Annual Meeting that is currently taking place in Orlando, Florida. The data were released today in three poster presentations. These presentations are further detailed below:
"You are what you eat." Can these pithy words explain the evolution of the human species?
A group of Senate Democrats will meet with President Obama today to discuss overhauling health care, The New York Times reports.
PharmAthene, Inc. (NYSE Amex: PIP), a biodefense company developing medical countermeasures against biological and chemical threats, announced that it has submitted a proposal to the Biomedical Advanced Research and Development Authority (BARDA) in response to a Broad Agency Announcement (BAA-BARDA-09-34) for advanced research and development of medical countermeasures for chemical, biological, radiological and nuclear threats. PharmAthene has requested funding to further develop Valortim(R), a fully human monoclonal antibody, for the prevention and treatment of anthrax infection. To date, the Company has received funding commitments from the U. S. government totaling up to $24 million to advance the development of Valortim(R).
Hyperion Therapeutics, Inc. announced top-line results from a phase I study of HPN-100 in patients with liver cirrhosis. The data were presented as part of the 2009 Digestive Disease Week meeting. The abstract is titled "Pharmacokinetic (PK) and Safety Analyses of a Novel Ammonia-Reducing Agent in Healthy Adults and Patients with Cirrhosis."
Roswell Park Cancer Institute (RPCI) scientists are investigating a promising drug for chronic myeloid leukemia (CML) patients who have become intolerant or resistant to standard therapies. Meir Wetzler, MD, Department of Medicine at Roswell Park Cancer Institute, analyzed the effectiveness of omacetaxine (OM) in an ongoing phase II clinical study and will present the findings at the American Society of Clinical Oncology (ASCO) 2009 annual meeting, May 29 - June 2, in Orlando, FL.
Researchers at Intermountain Medical Center in Salt Lake City believe that they have made a breakthrough connection between atrial fibrillation, a fairly common heart rhythm disorder, and Alzheimer"s disease, the leading form of dementia among Americans.
As swine flu spread from Mexico to Texas and then fanned out farther in the United States, Americans began to alter their behavior. Families kept children home from school, postponed trips to the mall, and stayed home instead of eating out. In so doing, the American population may have inadvertently altered the behavior of the pathogen itself.
Scientists are reporting two findings that could influence the way researchers screen for, treat and assess prognosis for women with locally advanced breast cancer, an aggressive form of the disease. One finding offers a critical message regarding treatment strategy, they say.
Privately owned UK biotech company
Merck Sharp & Dohme Limited (MSD) announced that the Medicines and Healthcare products Regulatory Agency (MHRA) has implemented the harmonised Summary of Product Characteristics (SmPCs) for "Cozaar"® (losartan potassium) and "Cozaar"®-Comp (losartan potassium/ hydrochlorothiazide) into the U.K. Marketing Authorisation following a European Commission (EC) Decision.
Data from the Phase III ZODIAC1 study in advanced non-small cell lung cancer patients, with the investigational drug vandetanib, were presented today at the American Society of Clinical Oncology (ASCO) meeting in Orlando. Results show that the study met its primary endpoint, demonstrating that the addition of vandetanib to docetaxel resulted in a statistically significant improvement in progression-free survival (PFS), the length of time a patient lives without their cancer growing (hazard ratio [HR] 0.79, 97.58% CI 0.70-0.90; PAbout vandetanib
Dr Peter O"Meara, Associate Professor in Pre-hospital Care at Charles Sturt University in Australia, is the first non-UK paramedic to be appointed to a three year visiting Professor post in the UK in the subject of Pre-Hospital Care.
Travelers book plane tickets online, bank customers can check their accounts at any computer, and busy families can grocery shop online. Someday, even doctor visits could be among the conveniences offered via the Internet. Researchers considering the feasibility and effectiveness of virtual doctors visits report that patients and physicians found that evaluations done through videoconferencing were similar to face-to-face visits on most measures, according a study published in the May issue of the Journal of Telemedicine and Telecare.
Despite what some may think, people aren"t hiding their use of BOTOX® Cosmetic and hyaluronic acid dermal fillers. In fact, according to survey statistics released today by The Aesthetic Surgery Education & Research Foundation (ASERF), the research arm of the American Society for Aesthetic Plastic Surgery (ASAPS), nearly nine out of 10 respondents (87 percent) openly discuss their BOTOX® Cosmetic and hyaluronic acid dermal filler treatments with others, with seven out of ten (70 percent) receiving support from the people they told.
An international team of astronauts, including Canadian Dr. Robert Thirsk who launched into space on May 27, have just published an article in the Canadian Medical Association Journal (CMAJ) about the complex physiologic changes and psychological effects that occur in space. They draw upon first-hand experience as both physician-astronauts and crew medical officers on space missions and from NASA literature and peer-reviewed medical s.
The BMA is stepping up its activity to publicise its concerns about government reforms that have created a market in healthcare and allowed commercially run firms to provide NHS care.
While most nutrition experts agree that school lunches should include more whole-grain products, a new study from the University of Minnesota finds that food-service workers lack understanding and the res to meet that goal.
Patients who have gastroesophageal reflux disease (GERD) for a prolonged period have an increased risk of developing Barrett"s esophagus, a pre-cancerous condition where the tissue lining the esophagus becomes damaged by stomach acid and transformed into something like the inside of the stomach. New research finds that radiofrequency ablation -- an endoscopic procedure involving targeted thermal energy -- was very successful at restoring the esophagus and reducing risk for cancer.
In a move intended to significantly accelerate the pace of MS research, the Multiple Sclerosis Society of Canada announced the establishment of five research and training centres involving over 100 established scientists and 250 trainees.
An over-the-counter prostate cancer test kit could be coming to a pharmacy near you, thanks to the collaborative work of a University of Central Florida chemist and M.D. Anderson Cancer Center Orlando researchers.
Research from the Johns Hopkins Children"s Center reveals that the drug most commonly used in type 2 diabetics who don"t need insulin works on a much more basic level than once thought, treating persistently elevated blood sugar - the hallmark of type 2 diabetes - by regulating the genes that control its production.
ATS Medical, Inc. (Nasdaq: ATSI), manufacturer and marketer of state-of-the-art cardiac surgery products and services, announced participation in the upcoming International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS) Meeting in San Francisco on June 3-6, 2009. The ISMICS meeting is a significant gathering of cardiovascular surgeons from around the world whose interests include the latest developments in less invasive forms of heart surgery. The annual ISMICS meeting provides an excellent venue for the Company to exhibit its growing portfolio of clinically relevant products designed to meet the needs of cardiac surgeons.
Researchers from the National Institutes of Health and other institutions have identified in mice two proteins essential for ovulation to take place.
Today, GlaxoSmithKline (GSK) announced the results of a Phase III study demonstrating that pazopanib reduced the risk of tumour progression or death by 54% compared to placebo.1
PRACE arranges a networking session during ISC"09. The session "PRACE: HPC for scientific
Although Supreme Court nominee Sonia Sotomayor"s confirmation hearings are more than a month away, "it"s easy to predict how they will go," New York Times columnist Ross Douthat writes. Douthat predicts that Senate Judiciary Committee members "will attempt to divine Sotomayor"s position on a variety of controversial topics," such as abortion rights, and in "a series of polite, evasive answers, the nominee will feign a studious neutrality on almost every issue that could come before her during what"s likely to be decades as one of the most powerful women in the world." According to Douthat, the "deeper stakes" that likely will be ignored are that "Sotomayor will be joining a high court that"s gradually become a kind of extra legislative body." He cites research from Harvard Law School professor Jed Shugerman showing that the court over roughly the past 50 years has invalidated both state and federal statutes at an unprecedented rate. Douthat also points to data from Evan Caminker of the University of Michigan showing that in one eight-year period, the court invalidated 16 federal laws in 5-4 votes, something that occurred only 25 times in the previous two centuries. Douthat writes that "settling so many vexing controversies with 5-to-4 votes -- effectively making Anthony Kennedy the nation"s philosopher king -- is an awfully poor way to run a republic."Douthat continues that the "modern court"s most enduringly controversial power grabs -- with Roe v. Wade leading the way -- were usually the work of liberal justices" but that "in practice, the main divide between liberal and conservative judges tends to be over the responsibilities of the federal government, not judicial activism per se." He writes, "There are bipartisan ways that the Court could be reined in, and the legislative branch reinvigorated," including the idea of a supermajority rule that would require a 6-3 vote to overturn federal legislation. This idea "might spur the court toward greater consensus, and perhaps greater modesty as well," according to Douthat. Another possibility would be to implement 12-year term limits, he says. Douthat concludes that these suggestions would not "reduce the Supreme Court"s power directly, but it would help us see the court for what it has become -- a deeply political institution, as fallible as any other, and answerable, when all is said and done, to us" (Douthat, New York Times, 6/2).
"Employer-provided medical insurance remains the bedrock of the nation"s health care system. And yet, while most big employers still provide health benefits, soaring premiums have meant many small businesses can no longer afford to cover their workers," the New York Times reports. Some are concerned that many such businesses, those with fewer than 100 workers and which employ 40 percent of the labor force, will be left out of the health reform plan incubating in Congress. While insurers have offered key concessions to make it easier for individuals to buy insurance, saying they"ll "sell policies even to people with pre-existing medical conditions, and to stop basing prices on how healthy or sick someone is," the companies appear unwilling to give small employers the same break.
The popular Nintendo Wii videogame system is helping radiology students reach new levels! Faculty from Weill Cornell Medical College have coupled the motion-sensitive Wii remote with the same computers used to analyze scans, and have found that the Wii remote makes examining CT and MRI images more ergonomic, heightens the interactivity during classes, and may potentially improve the ability to interpret scans.
Navajo County Public Health Services District officials announced today the first case of 2009 H1N1 in Navajo County. The Arizona Department of Health Services Lab confirmed that an 18 year old patient at Little Colorado Medical Center tested positive for the illness. The patient has subsequently been treated and released.
New findings throw light on how the brain heals itself and may change the way we think about treating chronic neurodegenerative diseases like Parkinson"s and Alzheimer"s.
GameStop (NYSE: GME) teamed with the National Women"s Health Re Center (NWHRC) to provide five key practical health tips for women in their 20s. The national video game retailer also asked 20-something celebrities Cote de Pablo (NCIS) and Michelle Trachtenberg (17 Again) to share their personal fitness tips as well. These tips and more health and fitness information can be found at http://www.gamestop.com/fitatanyage.
Cancer survivors of all ages will celebrate life on June 14 to show the world that life after a cancer diagnosis is not only possible, but it can be positive, productive and meaningful. From 10:30 a.m. to 5:00 p.m., in Bloch Cancer Survivors" Park on Harbor Island, cancer survivors, their families, healthcare professionals and the general public will take part in the 12th Annual Celebration of Life, hosted by Cancer Survivorship: San Diego!
Pfizer Inc announced today that Toviaz™ (fesoterodine fumarate) extended release tablets and the YourWay™ plan (http://www.ToviazYourWay.com), a comprehensive, customizable support plan for overactive bladder patients, are available in the United States. Toviaz is a once-daily prescription treatment for patients with symptoms of overactive bladder, which include frequent and sudden urges to urinate and wetting accidents. Toviaz works by helping to calm the bladder muscle that causes frequent, sudden urges to urinate.
It"s a curious paradox. Black adults are more likely to smoke than white adults and most smokers start as teenagers. But statistics show that fewer black youths than whites begin smoking as adolescents.
BioSante Pharmaceuticals, Inc. (NASDAQ: BPAX), which is developing a testosterone gel (LibiGel®) for the treatment of hypoactive sexual desire disorder (HSDD) in menopausal women, today commented on a paper published in the May 15, 2009 issue of AIDS, the Journal of the International AIDS Society, on the effect of testosterone in women infected with HIV. The peer-reviewed journal reported results of a randomized, placebo-controlled trial of testosterone in HIV-infected women indicating that long-term testosterone administration was well tolerated in HIV-infected women and resulted in significant improvement in body composition, bone mineral density (BMD), and quality of life indices.
Being overweight or obese does not make asthma worse in patients with mild and moderate forms of the disease, according to a study by National Jewish Health researchers, although it may reduce the response to medications.
Medical problems contributed to nearly two-thirds (62.1 percent) of all bankruptcies in 2007, according to a study in the August issue of the American Journal of Medicine that will be published online Thursday. The data were collected prior to the current economic downturn and hence likely understate the current burden of financial suffering. Between 2001 and 2007, the proportion of all bankruptcies attributable to medical problems rose by 49.6 percent. The authors" previous 2001 findings have been widely cited by policy leaders, including President Obama.
A new study appearing in Neurology and Urodynamics evaluates the use of a daytime diaper that uses a musical "wetting alarm" for children in day-care centers. The findings show that wetting alarm diaper training is an effective option for toilet training in a child-friendly way.
Ray Berkelbach is taking long walks three times a day just a couple weeks after having lung surgery. The 68-year-old retiree from Punta Gorda underwent robotic surgery at Moffitt Cancer Center to remove a cancerous part of his lung. His was the first lung procedure in the Tampa Bay area that used the robot-assisted da Vinci surgical system.
Hip resurfacing can be a good alternative to total hip replacement (THR) in young adults because it conserves bone and it has acceptable short- to medium-term results. However, there have been concerns about fractures of the femoral neck with this procedure, partly due to notching and varus alignment during implantation.
A national public health campaign in France was associated with a marked
With children having easier access to media and a wider variety of content, the possible negative influence on health issues such as sex, drugs, obesity and eating disorders is increased, and warrants monitoring usage and limiting access if necessary, according to a commentary in the June 3 issue of JAMA, a theme issue on child and adolescent health.
A protein related to aggressive cancers can actually improve the efficacy of gemcitabine at treating pancreatic cancer, according to a Priority Report in Cancer Research, published by researchers at Thomas Jefferson University.
When added to the mix, a new experimental drug known as TMC207 appeared to make a cocktail of background drugs five times more powerful